Recurrent implantation failure may identified after three failed IVF cycles or after transfer of 10 high grade embryos. There are many different factors which may contribute for this recurrent IVF failure , such as parental chromosomal translocations, abnormal uterine anatomy , hydrosalpinx, or inadequate culture conditions or embryo transfer techniques. Failure may be due to factors with the “Seed,Soil or the Cultivator” Some studies have suggested that local injury of the endometrium by means of a catheter or hysteroscopy can induce an inflammatory response that may facilitate the preparation for implantation. Artificial rupture of the covering of the embryo ( Zona pellucida) may improve implantation: Assisted Hatching , but is still not proved. Pre-implantation genetic screening of the embryos is now a day used to get and select best embryos. But this strategy did not show any improvement in patie...